Jewel Banik

PhD Candidate in Biomedical Sciences



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Jewel Banik

PhD Candidate


Curriculum vitae


Neurobiology and Developmental Sciences

University of Arkansas for Medical Sciences

UAMS Graduate School
4301 West Markham St., Slot #601
Little Rock, AR 72205




Jewel Banik

PhD Candidate in Biomedical Sciences


Neurobiology and Developmental Sciences

University of Arkansas for Medical Sciences

UAMS Graduate School
4301 West Markham St., Slot #601
Little Rock, AR 72205



About


  
I am a fourth-year Ph.D. graduate student in the Department of Neurobiology and Developmental Sciences at the University of Arkansas for Medical Sciences (UAMS). I received my Bachelor of Science (BS) in Pharmaceutical Sciences from North South University in Bangladesh. My current research focuses on the role of Musashi and regulated mRNA translation in pituitary development and function. To test the hypothesis, I am developing a mouse model using Cre-LoxP technology to selectively delete Musashi 1 and Musashi 2 encoding genes from Prop1 descendent cells in the anterior pituitary to explore Musashi’s role in vivo. In addition, I am utilizing Next-Generation Sequencing (NGS), qRT-PCR, and immunocytochemistry to generate a pituitary transcriptome profile, and detect the changes in hormonal content and the expression of pituitary-specific genes in Musashi-mutants. Moreover, I am investigating molecular mechanisms involved in Musashi 1, Musashi 2, and downstream target mRNAs in the pituitary using ribonucleoprotein (RNP) pulldown and mass spectrometry to assess protein-mRNA interaction and mRNA translation reporter in vitro assays. 

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